Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[2-(3,4-Dimethylphenoxy)Acetyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of critical importance for research and development in the synthesis of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. It is primarily needed by pharmaceutical R&D laboratories, process development chemists, and manufacturers specializing in the production of complex, high-value therapeutic agents.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: Serves as a crucial building block in the synthesis of next-generation antibacterial agents.
• Pharmaceutical R&D: Used in medicinal chemistry for the discovery and optimization of new drug candidates targeting bacterial infections.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for API manufacturing.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions.
• Custom Synthesis: A starting material for the preparation of structurally related analogs for biological screening.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[2-(3,4-Dimethylphenoxy)Acetyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	1054129-67-7
Molecular Formula	C27H27FN3O4
Molecular Weight	476.52 g/mol
Synonyms	1-Cyclopropyl-7-[4-[2-(3,4-dimethylphenoxy)acetyl]piperazin-1-yl]-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-7-(4-[(3,4-dimethylphenoxy)acetyl]piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; WCK 771; WCK-771; WCK771; Antibacterial Intermediate WCK 771; Advanced Fluoroquinolone Intermediate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Assay	97.0% - 102.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.