Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-7-[4-(1-Oxo-2-Phenylbutyl)-1-Piperazinyl]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel fluoroquinolone antibiotics, offering a key building block for research and development in antimicrobial therapies. It is primarily required by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical producers targeting the global API market.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of next-generation fluoroquinolone antibiotic active pharmaceutical ingredients (APIs).
• Antimicrobial Research: Used in medicinal chemistry for developing new antibacterial agents with improved efficacy and spectrum of activity.
• Process Chemistry: Serves as a critical starting material or intermediate in scale-up and process optimization for API manufacturing.
• Contract Manufacturing: Supplied to CMOs and CDMOs for the production of proprietary antibiotic compounds under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) in quinolone chemistry.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-7-[4-(1-Oxo-2-Phenylbutyl)-1-Piperazinyl]-
CAS No.	1054111-08-8
Molecular Formula	C27H26FN3O4
Molecular Weight	475.52 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-(1-oxo-2-phenylbutyl)-1-piperazinyl]-3-quinolinecarboxylic acid; 7-[4-(1-Oxo-2-phenylbutyl)-1-piperazinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid; Garenoxacin Intermediate; Garenoxacin Related Compound; AM-1155 Intermediate; OPC-17116 Intermediate; T-3811 Intermediate; (7S)-7-[(3S)-3-(1-Aminoethyl)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods (IR, NMR, MS). We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing all critical quality attributes. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.