Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-[2-[(4-Methylphenyl)Thio]Acetyl]-1-Piperazinyl]-4-Oxo- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation antibacterial or targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel quinolone and fluoroquinolone antibiotic candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug potency and pharmacokinetic properties.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical testing.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific drug discovery projects.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-[2-[(4-Methylphenyl)Thio]Acetyl]-1-Piperazinyl]-4-Oxo-
CAS No.	1054011-31-2
Molecular Formula	C26H26FN3O3S
Molecular Weight	479.57 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[4-[2-[(4-methylphenyl)thio]acetyl]-1-piperazinyl]-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-7-(4-((2-(p-tolylthio)acetyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1054011-31-2; UNII-9V8P1C8Q4F; 9V8P1C8Q4F; CHEMBL3185982; AKOS025147065; A-966492 (related analog).
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.