Description

3-Quinolinecarboxylic Acid, 7-[4-(2-Chloro-4-Fluorobenzoyl)-1-Piperazinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo- CAS NO 1054010-14-8 is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel quinolone and fluoroquinolone-based antibiotic candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new molecules with targeted biological activity.
• API Development: Serves as a crucial precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Biochemical Research: Potential use as a tool compound in biochemical assays to study bacterial enzyme inhibition.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 7-[4-(2-Chloro-4-Fluorobenzoyl)-1-Piperazinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	1054010-14-8
Molecular Formula	C24H20ClF2N3O3
Molecular Weight	471.89 g/mol
Synonyms	7-[4-(2-Chloro-4-fluorobenzoyl)piperazin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-7-[4-(2-chloro-4-fluorobenzoyl)-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid; WCK 771 Intermediate; Levonadifloxacin Intermediate; (S)-(-)-9-Fluroro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic Acid L-Alanine Ester (related); Benzo[i,j]quinolizine-2-carboxylic Acid Derivative; Antibacterial Quinolone Intermediate.
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.