Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-(2,3-Dimethylbenzoyl)-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is a key synthetic precursor in the development of novel fluoroquinolone antibiotics, offering critical structural complexity for targeted therapeutic applications. It is essential for R&D laboratories and pharmaceutical manufacturers engaged in the synthesis of next-generation antibacterial agents and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel fluoroquinolone-class antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for new antibacterial drug candidates.
• Chemical Synthesis & Process Chemistry: Serves as a versatile scaffold for creating structurally complex molecules in medicinal chemistry.
• Biochemical Research: Employed in studies investigating bacterial DNA gyrase and topoisomerase IV inhibition mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of pharmaceutical actives.
• Reference Standard: Used as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-(2,3-Dimethylbenzoyl)-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	1054009-42-5
Molecular Formula	C24H24FN3O3
Molecular Weight	421.47 g/mol
Synonyms	1-Cyclopropyl-7-[4-(2,3-dimethylbenzoyl)piperazin-1-yl]-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(2,3-dimethylbenzoyl)-1-piperazinyl)-3-quinolinecarboxylic Acid; WCK 2349 Intermediate; (1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid) derivative; 7-(4-(2,3-Dimethylbenzoyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; Fluoroquinolone Intermediate; Antibacterial Intermediate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. All materials undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and residual solvents is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.