Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-[2-(2-Naphthalenyl)Acetyl]-1-Piperazinyl]-4-Oxo- is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. This complex heterocyclic compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. It is primarily required by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of next-generation antibacterial agents and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel fluoroquinolone antibiotics and other therapeutic molecules.
• Antibacterial Drug Research: Used in R&D for developing new antibacterial agents targeting resistant bacterial strains.
• Chemical Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Development: Utilized in scaling up and optimizing synthetic routes for API manufacturing under cGMP conditions.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions.
• Academic Research: Used in university and institutional labs for studying heterocyclic chemistry and drug mechanisms.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-[2-(2-Naphthalenyl)Acetyl]-1-Piperazinyl]-4-Oxo-
CAS No.	1053952-34-3
Molecular Formula	C29H26FN3O4
Molecular Weight	499.54 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[4-[2-(naphthalen-2-yl)acetyl]piperazin-1-yl]-4-oxoquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-7-(4-(2-(naphthalen-2-yl)acetyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Garenoxacin Intermediate; Garenoxacin Related Compound; AM-1155 Intermediate; T-3811 Intermediate; BMS-284756 Intermediate; 7-(4-(2-(2-Naphthyl)acetyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities to meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Assay	97.0% - 102.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.