Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-[2-(4-Methylphenoxy)-1-Oxopropyl]-1-Piperazinyl]-4-Oxo- is a high-purity advanced pharmaceutical intermediate (API intermediate) with a complex heterocyclic structure. This compound is of critical importance for research and development in the synthesis of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. It is primarily needed by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in antimicrobial drug discovery and process chemistry.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: Serves as a crucial building block in the synthesis of next-generation broad-spectrum antibacterial agents.
• Pharmaceutical R&D: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling up production for clinical trial material and commercial API manufacturing.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical development.
• Academic Research: Utilized in university and institutional labs for studying antibacterial mechanisms and resistance.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-[2-(4-Methylphenoxy)-1-Oxopropyl]-1-Piperazinyl]-4-Oxo-
CAS No.	1053951-94-2
Molecular Formula	C27H28FN3O5
Molecular Weight	493.53 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[4-[2-(4-methylphenoxy)-1-oxopropyl]-1-piperazinyl]-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-7-(4-(2-(p-tolyloxy)propionyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Garenoxacin Intermediate; Garenoxacin Related Compound; AM-1155 Intermediate; T-3811 Intermediate; 7-(4-(2-(4-Methylphenoxy)propionyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.