Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[(5,6-Dihydro-4H-Cyclopenta[B]Thien-2-Yl)Carbonyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, complex heterocyclic compound designed for advanced pharmaceutical research and development. This molecule serves as a critical advanced pharmaceutical intermediate (API) in the synthesis of novel therapeutic agents. It is primarily targeted at pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) engaged in developing next-generation medications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel antibacterial agents, particularly fluoroquinolone-class antibiotics.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step manufacturing process of complex drug substances.
• Biochemical Research: Employed as a tool compound in biochemical assays to study bacterial enzyme inhibition (e.g., DNA gyrase, topoisomerase IV).
• Contract Manufacturing: Supplied to CMOs for the scale-up and cGMP production of investigational new drugs (INDs).

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[(5,6-Dihydro-4H-Cyclopenta[B]Thien-2-Yl)Carbonyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	1053951-63-5
Molecular Formula	C24H22FN3O3S
Molecular Weight	451.51 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-7-(4-(5,6-dihydro-4H-cyclopenta[b]thiophene-2-carbonyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; WCK 771; WCK-771; WCK771; Levonadifloxacin Intermediate; Levonadifloxacin Impurity; Alalevonadifloxacin Intermediate; (1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazinyl-3-quinolinecarboxylic acid, 4'-(5,6-dihydro-4H-cyclopenta[b]thiophene-2-carbonyl) derivative)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and regulatory support. We can supply material suitable for research use or manufactured under conditions supportive of cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.