Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-[(5-Nitro-2-Thienyl)Carbonyl]-1-Piperazinyl]-4-Oxo- is a high-purity, complex heterocyclic compound serving as a critical advanced pharmaceutical intermediate. Its intricate molecular structure makes it an essential building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. This product is primarily targeted at R&D laboratories and manufacturing facilities in the global pharmaceutical and fine chemical industries seeking reliable, high-quality raw materials for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the research and commercial synthesis of next-generation antibacterial agents, specifically fluoroquinolone derivatives.
• Chemical Research & Development: Serves as a sophisticated scaffold for medicinal chemists exploring new molecular entities with targeted biological activity.
• API Synthesis: Used in the multi-step manufacturing process of active pharmaceutical ingredients requiring a specific quinoline-carboxylic acid core structure.
• Biochemical Research: Potential tool compound for studying bacterial enzyme inhibition mechanisms, such as DNA gyrase and topoisomerase IV.
• Fine Chemical Production: Employed in the production of other high-value, specialized chemicals where its unique nitro-thienyl-piperazine moiety is required.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-[(5-Nitro-2-Thienyl)Carbonyl]-1-Piperazinyl]-4-Oxo-
CAS No.	1053951-26-0
Molecular Formula	C22H20FN5O5S
Molecular Weight	477.49 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[4-[(5-nitro-2-thienyl)carbonyl]-1-piperazinyl]-4-oxo-3-quinolinecarboxylic acid; 7-[4-(5-Nitro-2-thiophenecarbonyl)-1-piperazinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; Garenoxacin Intermediate; Garenoxacin Related Compound; (1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazin-1-yl-quinoline-3-carboxylic acid)-5-nitrothiophene-2-carboxylic acid piperazide; AM-1155 Intermediate; BMS-284756 Intermediate; T-3811 Intermediate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.