Description

1-n-Boc-1-Hydrazinoacetaldehyde Diethyl Acetal is a specialized, high-purity building block used in advanced organic synthesis. This compound matters as a key reagent for introducing protected hydrazino and aldehyde functionalities, enabling the construction of complex heterocycles and active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel compounds.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of nitrogen-containing heterocycles, such as pyrazoles and triazoles, found in drug candidates.
• Peptidomimetic Synthesis: Used to incorporate hydrazine-based linkers and aldehyde handles into peptide analogs and protein conjugates.
• Agrochemical Research: Serves as a precursor in developing novel herbicides, fungicides, and plant growth regulators with specific biological activity.
• Cross-linking Agent: Utilized in polymer chemistry and material science to create cross-linked networks or functionalized surfaces via its reactive aldehyde group.
• Chemical Biology Probes: Enables the labeling and study of biomolecules through bioorthogonal reactions involving protected hydrazines.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke, multi-step synthetic routes on a laboratory to pilot scale.

Basic Information

Product Name	1-n-Boc-1-Hydrazinoacetaldehyde Diethyl Acetal
CAS No.	1053659-75-8
Molecular Formula	C11H24N2O4
Molecular Weight	248.32 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-1-hydrazinoacetaldehyde diethyl acetal; N-Boc-hydrazinoacetaldehyde diethyl acetal; (1,1-Diethoxy-2-((2-(tert-butoxycarbonyl)hydrazinyl)methyl)ethene); tert-Butyl (1,1-diethoxy-2-oxoethyl)carbazate (acetal form); Boc-NHNH-CH2-CH(OEt)2; 2-((tert-Butoxycarbonyl)amino)-2-(diethoxymethyl)diazene 1-oxide (tautomeric form); 1-Boc-hydrazinoacetaldehyde DEA; 1-Boc-1-hydrazinoacetaldehyde diethyl acetal
EINECS	Contact for details

Quality Control

Our 1-n-Boc-1-Hydrazinoacetaldehyde Diethyl Acetal is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.