Description

N'-[2-Phenoxy-1-(2,2,2-Trifluoroethylamino)Ethylid Ene]Hydrazinecarboxylic Acid tert-Butyl Ester CAS NO 1053657-91-2 is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoroethylamino and hydrazinecarboxylate functional groups. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs) in medicinal chemistry research and development.
• Protease Inhibitor Synthesis: Serves as a crucial precursor in the development of protease inhibitors, a major class of antiviral and anticancer agents.
• Agrochemical Research: Used in the discovery and development of new agrochemicals, including herbicides and pesticides, leveraging its unique fluorine-containing structure.
• Chemical Biology Probes: Employed in the design and synthesis of chemical probes for studying enzyme function and biological pathways in academic and industrial research.
• Peptidomimetic Development: Integral to creating peptidomimetics—molecules that mimic peptides—for enhanced stability and bioavailability in drug candidates.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized fluorinated intermediates.

Basic Information

Product Name	N'-[2-Phenoxy-1-(2,2,2-Trifluoroethylamino)Ethylid Ene]Hydrazinecarboxylic Acid tert-Butyl Ester
CAS No.	1053657-91-2
Molecular Formula	C15H20F3N3O3
Molecular Weight	347.33 g/mol
Synonyms	tert-Butyl N'-[1-[(2,2,2-trifluoroethyl)amino]-2-phenoxyethylidene]hydrazinecarboxylate; 1-(2,2,2-Trifluoroethylamino)-2-phenoxyethylidene Hydrazinecarboxylic Acid tert-Butyl Ester; BOC-Hydrazide Trifluoroethyl Phenoxy Derivative; (Z)-tert-Butyl (1-((2,2,2-trifluoroethyl)amino)-2-phenoxyethylidene)carbazate; N'-(1-((2,2,2-Trifluoroethyl)amino)-2-phenoxyethylidene)hydrazinecarboxylic Acid tert-Butyl Ester; CAS 1053657-91-2
EINECS	Contact for details

Quality Control

Our N'-[2-Phenoxy-1-(2,2,2-Trifluoroethylamino)Ethylid Ene]Hydrazinecarboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.