Description

N'-[1-Cyclopentylamino-2-(4-Methoxyphenyl)Ethylide Ne]Hydrazinecarboxylic Acid tert-Butyl Ester is a sophisticated chiral building block and advanced pharmaceutical intermediate of significant interest in modern organic synthesis. Its value lies in its complex molecular architecture, which incorporates multiple functional handles for selective chemical transformations, enabling the construction of high-value target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly within medicinal chemistry programs. The CAS number for this material is 1053657-57-0.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) or metabolic disorder targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery pipelines.
• Asymmetric Synthesis: Utilized in the synthesis of complex, enantiomerically pure molecules due to its inherent chiral centers and protected functional groups.
• Peptidomimetic Development: The hydrazinecarboxylic acid ester moiety makes it valuable for constructing non-peptide mimics of biologically active peptides.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.

Basic Information

Product Name	N'-[1-Cyclopentylamino-2-(4-Methoxyphenyl)Ethylide Ne]Hydrazinecarboxylic Acid tert-Butyl Ester
CAS No.	1053657-57-0
Molecular Formula	C19H29N3O3
Molecular Weight	347.46 g/mol
Synonyms	tert-Butyl N'-[1-(cyclopentylamino)-2-(4-methoxyphenyl)ethylidene]hydrazinecarboxylate; 1-(Cyclopentylamino)-2-(4-methoxyphenyl)ethan-1-one tert-Butyl Carbazate Schiff Base; (1Z)-1-(Cyclopentylamino)-2-(4-methoxyphenyl)ethan-1-one O-tert-Butyl Carbazate; 1053657-57-0; BOC-Hydrazone Derivative; Chiral Schiff Base Intermediate; tert-Butyl (1Z)-[1-(cyclopentylamino)-2-(4-methoxyphenyl)ethylidene]carbazate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols suitable for research and pharmaceutical applications. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, chiral purity, and chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality management system supports compliance with relevant guidelines for investigational materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.