Description

N'-[2-(4-Chlorophenyl)-1-Cyclopropylaminoethyliden E]Hydrazinecarboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) focused on developing new drugs, particularly in areas requiring sophisticated heterocyclic and hydrazine-based chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the production route of complex active pharmaceutical ingredients that incorporate cyclopropyl and hydrazine functional groups.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Chemical Biology Probes: Can be utilized in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Item	Details
Product Name	N'-[2-(4-Chlorophenyl)-1-Cyclopropylaminoethyliden E]Hydrazinecarboxylic Acid tert-Butyl Ester
CAS No.	1053657-43-4
Molecular Formula	C₁₆H₂₂ClN₃O₂
Molecular Weight	323.82 g/mol
Synonyms	tert-Butyl N'-[2-(4-chlorophenyl)-1-(cyclopropylamino)ethylidene]hydrazinecarboxylate; (E)-tert-Butyl 2-(2-(4-chlorophenyl)-1-(cyclopropylamino)ethylidene)hydrazine-1-carboxylate; 1053657-43-4; tert-Butyl (E)-[2-(4-chlorophenyl)-1-(cyclopropylamino)ethylidene]carbazate; N'-(2-(4-Chlorophenyl)-1-(cyclopropylimino)ethyl)hydrazinecarboxylic Acid tert-Butyl Ester; (1E)-2-(4-Chlorophenyl)-N-cyclopropyl-1-[2-[(1,1-dimethylethoxy)carbonyl]hydrazinylidene]ethanamine
EINECS	Contact for details

Quality Control

Our N'-[2-(4-Chlorophenyl)-1-Cyclopropylaminoethyliden E]Hydrazinecarboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.