Description

5-tert-Butyl 1-Ethyl 3-Amino-3A,4,6,6A-Tetrahydropyrrolo[3,4-C]Pyrazole-1,5-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyrazole chemical class. This compound is critical for research and development in medicinal chemistry, serving as a sophisticated building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis to discover new bioactive molecules.
• API Development: Integral in the process development and scale-up stages for new active pharmaceutical ingredients.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for cutting-edge research in heterocyclic and synthetic organic chemistry.
• Bioconjugation & Probe Synthesis: Potential use in creating chemical probes or tagged molecules for biochemical and diagnostic applications.

Basic Information

Item	Details
Product Name	5-tert-Butyl 1-Ethyl 3-Amino-3A,4,6,6A-Tetrahydropyrrolo[3,4-C]Pyrazole-1,5-Dicarboxylate
CAS No.	1053656-67-9
Molecular Formula	C15H24N4O4
Molecular Weight	324.38 g/mol
Synonyms	1,5-Dicarboxylic acid, 3-amino-3a,4,6,6a-tetrahydropyrrolo[3,4-c]pyrazole-1,5-diester, 5-tert-butyl 1-ethyl; 5-(tert-Butyl) 1-ethyl 3-amino-3a,4,6,6a-tetrahydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate; tert-Butyl ethyl 3-amino-3a,4,6,6a-tetrahydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate; Fused Pyrrolopyrazole Derivative; 3-Aminopyrrolopyrazole diester; BOC-Protected Pyrrolopyrazole Intermediate
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl 1-Ethyl 3-Amino-3A,4,6,6A-Tetrahydropyrrolo[3,4-C]Pyrazole-1,5-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.