Description

7-Benzyl-5,6,7,8-Tetrahydropyrido-[3,4-D]Pyrimidin-4(3H)-One Hydrochloride is a high-purity pharmaceutical intermediate and research chemical with the CAS registry number 1053656-41-9. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex heterocyclic molecules. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in drug discovery programs, particularly those targeting kinase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme function and cellular signaling pathways.
• Academic Research: Employed in university and institutional labs for exploratory organic synthesis and heterocyclic chemistry studies.
• Contract Research & Development (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	7-Benzyl-5,6,7,8-Tetrahydropyrido-[3,4-D]Pyrimidin-4(3H)-One Hydrochloride
CAS No.	1053656-41-9
Molecular Formula	C₁₆H₁₈N₄O·HCl
Molecular Weight	318.80 g/mol
Synonyms	7-Benzyl-3,4,5,6-tetrahydro-4-oxopyrido[3,4-d]pyrimidine hydrochloride; 7-Benzyl-4-hydroxy-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride; 4(3H)-Pyrimidinone, 7-benzyl-5,6,7,8-tetrahydro-, hydrochloride; 1053656-41-9; 7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-ol hydrochloride; 7-Benzyl-4-oxo-3,4,5,6,7,8-hexahydro-pyrido[3,4-d]pyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our 7-Benzyl-5,6,7,8-Tetrahydropyrido-[3,4-D]Pyrimidin-4(3H)-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure compliance with research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.