Description

N'-[1-Amino-2-(2-Chlorophenyl)Ethylidene]-Hydrazinecarboxylic Acid tert-Butyl Ester is a sophisticated organic building block, specifically a protected hydrazine derivative, designed for advanced synthetic chemistry. Its primary value lies in serving as a critical intermediate for the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs), enabling precise molecular construction. This high-purity intermediate is essential for research and development chemists and process scale-up teams within the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing hydrazide or pyrazole core structures.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its chlorophenyl moiety is a valuable structural component.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecules via reactions involving its reactive amino and hydrazine functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands used in catalysis and material science.
• Peptidomimetic Research: The tert-butyloxycarbonyl (Boc) protected hydrazine group makes it useful in the design of peptide analogs and enzyme inhibitors.

Basic Information

Item	Details
Product Name	N'-[1-Amino-2-(2-Chlorophenyl)Ethylidene]-Hydrazinecarboxylic Acid tert-Butyl Ester
CAS No.	1053656-05-5
Molecular Formula	C₁₃H₁₈ClN₃O₂
Molecular Weight	283.75 g/mol
Synonyms	tert-Butyl N'-[1-amino-2-(2-chlorophenyl)ethylidene]hydrazinecarboxylate; 1-Amino-2-(2-chlorophenyl)ethan-1-one tert-butyl hydrazonecarboxylate; (1-Amino-2-(2-chlorophenyl)ethylidene)hydrazinecarboxylic acid tert-butyl ester; 2-Chloro-α-(N-Boc-hydrazono)acetophenone; Boc-Hydrazone of 2-Chloro-α-aminoacetophenone
EINECS	Contact for details

Quality Control

Our N'-[1-Amino-2-(2-Chlorophenyl)Ethylidene]-Hydrazinecarboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.