Description

N'-[1-Amino-1-(3-Fluoro-4-Methylphenyl)Methylidene ]Hydrazinecarboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex organic synthesis. This compound is critical for research and development in medicinal chemistry, particularly in the construction of novel heterocyclic scaffolds and active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging its fluorinated aromatic structure for enhanced biological activity and stability.
• Material Science: Serves as a precursor for specialized polymers and liquid crystals, where its molecular structure can impart specific optical or electronic properties.
• Academic & Contract Research: Essential for methodological studies in organic synthesis, including palladium-catalyzed cross-coupling reactions and hydrazone chemistry.
• Peptidomimetics: Employed in the design and synthesis of peptide analogs and protease inhibitors due to its hydrazinecarboxylic acid ester moiety.

Basic Information

Product Name	N'-[1-Amino-1-(3-Fluoro-4-Methylphenyl)Methylidene ]Hydrazinecarboxylic Acid tert-Butyl Ester
CAS No.	1053655-97-2
Molecular Formula	C13H18FN3O2
Molecular Weight	267.30 g/mol
Synonyms	tert-Butyl (2E)-2-[(1Z)-1-amino-1-(3-fluoro-4-methylphenyl)methylidene]hydrazinecarboxylate; (E)-tert-Butyl 2-((Z)-(1-amino-1-(3-fluoro-4-methylphenyl)methylidene)hydrazinecarboxylate; 1-(3-Fluoro-4-methylphenyl)-1-amino-methanone tert-butyl hydrazonecarboxylate; tert-Butyl N'-[(1Z)-1-amino-1-(3-fluoro-4-methylphenyl)methylidene]carbazate; BOC-Hydrazone of 3-Fluoro-4-methylbenzamidine; 1053655-97-2
EINECS	Contact for details

Quality Control

Our production of N'-[1-Amino-1-(3-Fluoro-4-Methylphenyl)Methylidene ]Hydrazinecarboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.