Description

N'-[1-Amino-2-(2-Chlorophenoxy)Ethylidene]-Hydrazinecarboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for constructing molecules with specific biological activity. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates, particularly in research for central nervous system (CNS) and anti-infective agents.
• Medicinal Chemistry Research: Used as a specialized building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Integral in the production route for active pharmaceutical ingredients that require a hydrazinecarboxylate moiety in their molecular structure.
• Chemical Biology Probes: Serves as a starting material for creating labeled compounds or probes used in biochemical and pharmacological assays.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of bespoke organic compounds for client-specific projects.

Basic Information

Item	Details
Product Name	N'-[1-Amino-2-(2-Chlorophenoxy)Ethylidene]-Hydrazinecarboxylic Acid tert-Butyl Ester
CAS No.	1053655-91-6
Molecular Formula	C13H18ClN3O3
Molecular Weight	299.75 g/mol
Synonyms	tert-Butyl N'-[1-amino-2-(2-chlorophenoxy)ethylidene]hydrazinecarboxylate; 1-Amino-2-(2-chlorophenoxy)ethan-1-one tert-butyl carbazate; BOC-Hydrazide derivative of 2-chlorophenoxyacetamide; (Z)-tert-Butyl 2-(1-amino-2-(2-chlorophenoxy)ethylidene)hydrazine-1-carboxylate; 1053655-91-6; tert-Butyl (Z)-2-[1-amino-2-(2-chlorophenoxy)ethylidene]hydrazinecarboxylate
EINECS	Contact for details

Quality Control

Our N'-[1-Amino-2-(2-Chlorophenoxy)Ethylidene]-Hydrazinecarboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.