Description

N'-[1-Amino-2-(4-Methoxyphenoxy)Ethylidene]-Hydrazinecarboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a protected hydrazinecarboxylic acid moiety for precise molecular construction. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Protease Inhibitor Research: Used in the research and development of protease inhibitors, a major class of antiviral and anticancer drugs.
• Peptidomimetic Synthesis: Serves as a crucial precursor for creating peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.
• Chemical Biology Probes: Employed in the development of specialized chemical probes for studying enzyme mechanisms and protein-protein interactions.
• Scale-up Process Development: Supplied for process optimization and scale-up studies from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: Serves as a starting material for custom synthesis services targeting specific, high-value molecular targets for clients.

Basic Information

Product Name	N'-[1-Amino-2-(4-Methoxyphenoxy)Ethylidene]-Hydrazinecarboxylic Acid tert-Butyl Ester
CAS No.	1053655-77-8
Molecular Formula	C14H21N3O4
Molecular Weight	295.34 g/mol
Synonyms	tert-Butyl N'-[1-amino-2-(4-methoxyphenoxy)ethylidene]hydrazinecarboxylate; 1-Amino-2-(4-methoxyphenoxy)ethan-1-one tert-butyl carbazate; BOC-Hydrazide Derivative; (Z)-tert-Butyl 2-(1-amino-2-(4-methoxyphenoxy)ethylidene)hydrazine-1-carboxylate; N'-(1-Amino-2-(4-methoxyphenoxy)ethylidene)hydrazinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl (1Z)-2-[1-amino-2-(4-methoxyphenoxy)ethylidene]hydrazinecarboxylate; 1053655-77-8; BOC-protected hydrazone intermediate
EINECS	Contact for details

Quality Control

Our N'-[1-Amino-2-(4-Methoxyphenoxy)Ethylidene]-Hydrazinecarboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.