Description

N'-[1-Amino-1-(4-(Trifluoromethoxy)Phenyl)Methylid Ene]Hydrazinecarboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for constructing molecules with specific biological activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring trifluoromethoxy-substituted aromatic systems.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides that leverage the trifluoromethoxy group for enhanced efficacy and stability.
• Chemical Biology Probes: Utilized in the creation of specialized probes and ligands for studying biological targets and pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule assembly.
• Academic Research: Used in university and institutional labs for exploratory organic synthesis and methodological development.

Basic Information

Product Name	N'-[1-Amino-1-(4-(Trifluoromethoxy)Phenyl)Methylid Ene]Hydrazinecarboxylic Acid tert-Butyl Ester
CAS No.	1053655-71-2
Molecular Formula	C13H16F3N3O3
Molecular Weight	319.28 g/mol
Synonyms	tert-Butyl N'-[1-amino-1-[4-(trifluoromethoxy)phenyl]methylidene]hydrazinecarboxylate; 1-Amino-1-[4-(trifluoromethoxy)phenyl]methylidene Hydrazinecarboxylic Acid tert-Butyl Ester; (E)-tert-Butyl (2-(1-amino-1-(4-(trifluoromethoxy)phenyl)methylidene)hydrazinecarboxylate; BOC-Hydrazone Derivative of 4-(Trifluoromethoxy)benzaldehyde; (1E)-2-[(1,1-Dimethylethoxy)carbonyl]-2-[amino[4-(trifluoromethoxy)phenyl]methylene]hydrazine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Each batch is characterized and tested for identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for parameters such as assay, related substances, and residual solvents are available upon request. Our quality management system supports the stringent requirements of cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.