Description

2-(Chloromethyl)-8-Methylimidazo[1,2-A]Pyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for neurological and anti-infective applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting the central nervous system.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the multi-step synthesis of complex APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	2-(Chloromethyl)-8-Methylimidazo[1,2-A]Pyridine Hydrochloride
CAS No.	1052548-78-3
Molecular Formula	C10H10Cl2N2
Molecular Weight	229.10 g/mol
Synonyms	8-Methyl-2-(chloromethyl)imidazo[1,2-a]pyridine hydrochloride; Imidazo[1,2-a]pyridine, 2-(chloromethyl)-8-methyl-, hydrochloride; 2-(Chloromethyl)-8-methylimidazo[1,2-a]pyridine HCl; 8-Methyl-2-chloromethylimidazo[1,2-a]pyridine hydrochloride; 1052548-78-3 (CAS RN)
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-8-Methylimidazo[1,2-A]Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.