Description

2-(4-Methylphenylsulfonamido)-4-(Trifluoromethyl)Benzoic Acid is a high-purity, specialized organic intermediate of significant interest in advanced chemical synthesis. This compound is valued for its unique molecular architecture, which incorporates both a sulfonamide linkage and a trifluoromethyl group, making it a versatile building block for creating novel active molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and inflammatory pathways.
• Agrochemical Research: Serves as a critical building block for developing next-generation herbicides and fungicides, leveraging the bioactivity of the sulfonamide and trifluoromethyl motifs.
• Chemical Synthesis Reagent: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with specific thermal or surface properties.

Basic Information

Product Name	2-(4-Methylphenylsulfonamido)-4-(Trifluoromethyl)Benzoic Acid
CAS No.	1052490-28-4
Molecular Formula	C15H12F3NO4S
Molecular Weight	359.32 g/mol
Synonyms	2-[(4-Methylphenyl)sulfonylamino]-4-(trifluoromethyl)benzoic acid; 4-Methyl-N-[2-(trifluoromethyl)-4-carboxyphenyl]benzenesulfonamide; Benzoic acid, 2-[[(4-methylphenyl)sulfonyl]amino]-4-(trifluoromethyl)-; 2-(p-Tolylsulfonamido)-4-(trifluoromethyl)benzoic acid; 2-(Tosylamido)-4-(trifluoromethyl)benzoic acid; 1052490-28-4; 2-(4-Methylbenzenesulfonamido)-4-(trifluoromethyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Methylphenylsulfonamido)-4-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.