Description

6-(Trifluoromethoxy)Quinolin-3-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its quinoline core and trifluoromethoxy substituent. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular frameworks. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new drug candidates and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially in oncology, CNS, and anti-infective research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the quinoline scaffold.
• Material Science: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Synthesis: Employed in organic chemistry research for constructing complex heterocyclic compounds and fluorinated molecules.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalytic systems in asymmetric synthesis.

Basic Information

Product Name	6-(Trifluoromethoxy)Quinolin-3-Amine
CAS No.	1051372-65-6
Molecular Formula	C₁₀H₇F₃N₂O
Molecular Weight	228.17 g/mol
Synonyms	3-Amino-6-(trifluoromethoxy)quinoline; 6-(Trifluoromethoxy)-3-quinolinamine; 6-Trifluoromethoxyquinolin-3-ylamine; Quinolin-3-amine, 6-(trifluoromethoxy)-; 1051372-65-6; 6-(Trifluoromethoxy)-3-aminoquinoline; 3-Amino-6-trifluoromethoxyquinoline
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethoxy)Quinolin-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.