Description

[3-(Pentafluorophenoxy)Propyl]Amine Hydrochloride is a specialized fluorinated organic building block with a primary amine hydrochloride functionality. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, advanced materials, and ligand synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the pentafluorophenoxy group can influence binding affinity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis, including for cross-coupling reactions common in fine chemical manufacturing.
• Material Science Research: Employed in the synthesis of fluorinated polymers, dendrimers, or surface modifiers to impart unique hydrophobic or chemical resistance properties.
• Bioconjugation and Probe Synthesis: The amine hydrochloride group allows for coupling to carboxylic acids or activated esters, useful in creating fluorescent probes or biochemical tools.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring precise introduction of a fluorinated phenoxyalkylamine moiety.

Basic Information

Product Name	[3-(Pentafluorophenoxy)Propyl]Amine Hydrochloride
CAS No.	1051368-92-3
Molecular Formula	C9H9ClF5NO
Molecular Weight	277.62 g/mol
Synonyms	1-Amino-3-(pentafluorophenoxy)propane hydrochloride; 3-(Pentafluorophenoxy)-1-propanamine hydrochloride; 3-(Pentafluorophenoxy)propylamine HCl; Pentafluorophenoxypropylamine hydrochloride; 3-Aminopropyl pentafluorophenyl ether hydrochloride; γ-(Pentafluorophenoxy)propylamine hydrochloride; 1-Propanamine, 3-(2,3,4,5,6-pentafluorophenoxy)-, hydrochloride
EINECS	Contact for details

Quality Control

Our [3-(Pentafluorophenoxy)Propyl]Amine Hydrochloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing batch-specific results is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.