Description

3-Quinolinecarboxylic Acid, 7-[4-(3-Cyclohexyl-1-Oxopropyl)-1-Piperazinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo- is a complex, high-value pharmaceutical intermediate with a CAS number of 1051224-17-9. This compound is critical for the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in the development of novel antibacterial agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of next-generation fluoroquinolone antibiotics and other therapeutic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel fluoroquinolone antibiotic APIs.
• Antibacterial Drug Research: Used in R&D for developing new antibacterial agents with improved efficacy and spectrum of activity.
• Process Chemistry: Serves as a critical intermediate in scale-up and process optimization for commercial drug manufacturing.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore new quinoline-based therapeutic molecules.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 7-[4-(3-Cyclohexyl-1-Oxopropyl)-1-Piperazinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	1051224-17-9
Molecular Formula	C26H32FN3O4
Molecular Weight	469.55 g/mol
Synonyms	7-[4-(3-Cyclohexyl-1-oxopropyl)-1-piperazinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-7-[4-(3-oxo-3-cyclohexylpropyl)piperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Intermediate for Antibacterial Agents; Fluoroquinolone Intermediate; 1051224-17-9 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.