Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[2-(2,3-Dihydro-5-Benzofuranyl)Acetyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, complex heterocyclic compound with a CAS Registry Number of 1051224-11-3. This advanced pharmaceutical intermediate is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutic agents. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of next-generation medications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel, complex drug candidates, particularly for research into new therapeutic areas.
• API Development: Serves as a critical precursor in the research and development stages of new Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery programs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of pharmaceutical compounds.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and heterocyclic chemistry.
• Process Chemistry: Employed in the development and optimization of scalable synthetic routes for pharmaceutical production.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[2-(2,3-Dihydro-5-Benzofuranyl)Acetyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	1051224-11-3
Molecular Formula	C27H26FN3O4
Molecular Weight	475.52 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-7-(4-(2-(2,3-dihydrobenzofuran-5-yl)acetyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(2-(2,3-dihydro-5-benzofuranyl)acetyl)-1-piperazinyl)-3-quinolinecarboxylic Acid; UNII-9QZ80IQA8F; 9QZ80IQA8F; BCP31999; CHEMBL3183002; AKOS025147065; ZINC000004143756
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects requiring material that meets exacting internal or compendial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.