Description

2-Cyanoethyl 4-(4-Cyano-2-Methoxyphenyl)-2,8-Dimethyl-5-Oxo-1,4,5,6-Tetrahydro-1,6-Naphthyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules with improved efficacy and safety profiles.
• API Synthesis: Serves as a critical precursor in the production route for complex Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Employed in the development of chemical probes for studying biological processes and target validation in drug discovery.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in organic synthesis and drug discovery methodologies.

Basic Information

Item	Details
Product Name	2-Cyanoethyl 4-(4-Cyano-2-Methoxyphenyl)-2,8-Dimethyl-5-Oxo-1,4,5,6-Tetrahydro-1,6-Naphthyridine-3-Carboxylate
CAS No.	1050477-43-4
Molecular Formula	C24H22N4O4
Molecular Weight	430.46 g/mol
Synonyms	4-(4-Cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylic acid 2-cyanoethyl ester; 1,6-Naphthyridine-3-carboxylic acid, 1,4,5,6-tetrahydro-4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-, 2-cyanoethyl ester; 2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate; CAS 1050477-43-4; 1,6-Naphthyridine derivative; Tetrahydro-1,6-naphthyridine intermediate.
EINECS	Contact for details

Quality Control

Our 2-Cyanoethyl 4-(4-Cyano-2-Methoxyphenyl)-2,8-Dimethyl-5-Oxo-1,4,5,6-Tetrahydro-1,6-Naphthyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.