Description

n-Alloc-1,3-Propanediamine Hydrochloride is a protected diamine derivative, specifically the hydrochloride salt of the N-Alloc (allyloxycarbonyl) protected form of 1,3-diaminopropane. This compound is a crucial building block in organic synthesis and peptide chemistry, offering a versatile handle for selective amine protection and deprotection strategies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring selective modification of a diamine scaffold.
• Peptide Synthesis: Used as a protected diamine monomer in solid-phase and solution-phase peptide synthesis to introduce a 1,3-diaminopropane spacer or linker with orthogonal protecting group chemistry.
• Ligand and Catalyst Development: Acts as a precursor for creating chelating ligands and organocatalysts in asymmetric synthesis and metal complexation.
• Bioconjugation and Linker Chemistry: Employed in the design of cleavable linkers for antibody-drug conjugates (ADCs) and other bioconjugation applications.
• Polymer and Material Science: Functions as a monomer or cross-linking agent for the production of specialized polyamides, polyurethanes, and functionalized polymers.
• Agrochemical Research: Used in the research and development of new herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	n-Alloc-1,3-Propanediamine Hydrochloride
CAS No.	1049721-72-3
Molecular Formula	C7H15ClN2O2
Molecular Weight	194.66 g/mol
Synonyms	N-Alloc-1,3-diaminopropane hydrochloride; 1,3-Propanediamine, N1-[(phenylmethoxy)carbonyl]-, hydrochloride (1:1); N-[(Benzyloxy)carbonyl]-1,3-propanediamine hydrochloride; Z-1,3-Propanediamine hydrochloride; N-Cbz-1,3-propanediamine hydrochloride; N-[(Benzyloxy)carbonyl]propane-1,3-diamine hydrochloride; Alloc-protected 1,3-diaminopropane HCl; 3-[(Benzyloxycarbonyl)amino]propylamine hydrochloride
EINECS	Contact for details

Quality Control

Our n-Alloc-1,3-Propanediamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures material consistency and reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.