Description

4-Amino-8-(trifluoromethyl)-3-quinolinecarboxylic acid (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline scaffold and trifluoromethyl group. This compound matters for its critical role in the synthesis of novel, potent active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. Pharmaceutical R&D teams and fine chemical manufacturers need this building block to develop next-generation drugs, including potential antivirals, anticancer agents, and other specialized small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs) targeting various disease pathways.
• Antiviral Drug Development: Used in research and production of potential antiviral medications, leveraging the quinoline core's bioactivity.
• Oncology Research Compounds: Serves as a precursor in the creation of investigational small-molecule cancer therapies.
• Agrochemical Synthesis: Intermediate for developing advanced crop protection agents and pesticides with enhanced efficacy.
• Material Science Research: Used in the development of organic electronic materials and specialty dyes due to its conjugated structure.
• Chemical Biology Probes: Utilized in creating labeled compounds and probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	4-Amino-8-(trifluoromethyl)-3-quinolinecarboxylic Acid (Saltdata: Free)
CAS No.	1049127-39-0
Molecular Formula	C11H7F3N2O2
Molecular Weight	256.18 g/mol
Synonyms	4-Amino-8-(trifluoromethyl)quinoline-3-carboxylic Acid; 3-Quinolinecarboxylic acid, 4-amino-8-(trifluoromethyl)-; 8-(Trifluoromethyl)-4-aminoquinoline-3-carboxylic Acid; 4-Amino-8-trifluoromethylquinoline-3-carboxylic Acid; 1049127-39-0; 4-Amino-8-(trifluoromethyl)-3-quinolinecarboxylic acid free base
EINECS	Contact for details

Quality Control

Our 4-Amino-8-(trifluoromethyl)-3-quinolinecarboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.