Description

4-Amino-8-(Trifluoromethyl)Quinoline-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both an amino group and a trifluoromethyl substituent, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents. CAS No. 1049114-56-8.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, particularly for applications in oncology, anti-infectives, and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds, leveraging its reactive amino and ester functional groups.
• Fluorine Chemistry: A valuable substrate for studying structure-activity relationships (SAR) in fluorinated compounds due to its strategically placed trifluoromethyl group.

Basic Information

Product Name	4-Amino-8-(Trifluoromethyl)Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1049114-56-8
Molecular Formula	C₁₃H₁₁F₃N₂O₂
Molecular Weight	284.24 g/mol
Synonyms	Ethyl 4-Amino-8-(trifluoromethyl)quinoline-3-carboxylate; 4-Amino-8-trifluoromethylquinoline-3-carboxylic acid ethyl ester; 8-(Trifluoromethyl)-4-aminoquinoline-3-carboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 4-amino-8-(trifluoromethyl)-, ethyl ester; 1049114-56-8; 4-Amino-8-(trifluoromethyl)-3-quinolinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 4-Amino-8-(Trifluoromethyl)Quinoline-3-Carboxylic Acid Ethyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.