Description

5-Bromo-2-(Trifluoromethoxy)Phenol is a high-purity, halogenated phenolic compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and trifluoromethoxy substituents, makes it an essential intermediate for creating complex molecules with tailored properties. This product is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients, as well as in materials science for specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a core component in the synthesis of fluorine-containing liquid crystals for high-performance displays (LCDs).
• Polymer Science: Acts as a monomer or modifier in the creation of specialty polymers with enhanced thermal stability, chemical resistance, and unique optical properties.
• Organic Electronic Materials: Utilized in the development of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Chemical Research & Development: A valuable reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and for introducing halogenated phenolic motifs into complex molecular architectures.

Basic Information

Product Name	5-Bromo-2-(Trifluoromethoxy)Phenol
CAS No.	1048963-39-8
Molecular Formula	C7H4BrF3O2
Molecular Weight	257.01 g/mol
Synonyms	2-Bromo-5-(trifluoromethoxy)phenol; 5-Bromo-2-(trifluoromethoxy)phenol; 2-Hydroxy-4-bromo-1-(trifluoromethoxy)benzene; Phenol, 5-bromo-2-(trifluoromethoxy)-; 4-Bromo-2-(trifluoromethoxy)phenol (common numbering variation); 5-Bromo-α,α,α-trifluoro-2-guaiacol
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Trifluoromethoxy)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material is suitable for demanding applications in GMP-aligned pharmaceutical development and other high-value industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.