Description

5-(3-Chlorophenyl)-1H-Pyrrole-2-Carboxylic Acid is a high-purity, synthetically valuable heterocyclic building block. This compound is a critical intermediate in the research and development of novel active pharmaceutical ingredients (APIs), particularly for its role in constructing complex molecular scaffolds. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and advanced material scientists for applications in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its unique chlorophenyl-pyrrole structure.
• Material Science: Serves as a precursor for functional organic materials, including organic semiconductors and ligands for metal-organic frameworks (MOFs).
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening in drug discovery programs.
• Chemical Biology: Utilized as a probe or tag in biochemical research to study protein interactions and enzyme mechanisms.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	5-(3-Chlorophenyl)-1H-Pyrrole-2-Carboxylic Acid
CAS No.	1048917-65-2
Molecular Formula	C11H8ClNO2
Molecular Weight	221.64 g/mol
Synonyms	1H-Pyrrole-2-carboxylic acid, 5-(3-chlorophenyl)-; 3-Chloro-5-(1H-pyrrol-2-yl)benzoic acid; 5-(3-Chlorophenyl)-1H-pyrrole-2-carboxylic acid; 5-(m-Chlorophenyl)-1H-pyrrole-2-carboxylic acid; 2-Carboxy-5-(3-chlorophenyl)pyrrole; 1048917-65-2; 5-(3-Chlorophenyl)pyrrole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(3-Chlorophenyl)-1H-Pyrrole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.