Description

3-Nitro-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block characterized by its nitro and trifluoromethyl substituents. This compound is essential for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for creating targeted drug candidates, particularly in oncology and CNS therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted small-molecule therapeutics.
• Agrochemical Research: Used in developing advanced active ingredients with improved efficacy and environmental profiles.
• Material Science: Serves as a building block for functionalized polymers and advanced organic electronic materials.
• Chemical Biology: Employed in the design of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for client-specific projects.

Basic Information

Product Name	3-Nitro-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1048914-26-6
Molecular Formula	C8H4F3N3O2
Molecular Weight	231.14 g/mol
Synonyms	3-Nitro-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-nitro-5-(trifluoromethyl)-; 1048914-26-6; 3-Nitro-5-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; 5-(Trifluoromethyl)-3-nitro-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Nitro-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.