Description

(4-Fluorobenzyl)(Tetrahydro-2-Furanylmethyl)Amine Hydrochloride is a high-purity organic salt building block of significant interest in advanced chemical synthesis. This compound matters as a critical intermediate for the development of novel pharmaceuticals and agrochemicals, enabling the introduction of specific fluorinated and heterocyclic motifs. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom and amine hydrochloride moiety can enhance biological activity and stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and receptor interactions.
• Material Science Precursor: Potential use in the synthesis of advanced polymers or functional materials with specific electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales, from gram to kilogram quantities.

Basic Information

Product Name	(4-Fluorobenzyl)(Tetrahydro-2-Furanylmethyl)Amine Hydrochloride
CAS No.	1048640-49-8
Molecular Formula	C13H19ClFNO
Molecular Weight	259.75 g/mol
Synonyms	N-[(4-Fluorophenyl)methyl]-1-(tetrahydro-2-furanylmethyl)methanamine hydrochloride; 1-[(4-Fluorobenzyl)amino]methyltetrahydrofuran hydrochloride; Tetrahydrofurfuryl-(4-fluorobenzyl)amine hydrochloride; 4-Fluorobenzyl(tetrahydrofurfuryl)amine HCl; (4-Fluorobenzyl)(tetrahydrofuran-2-ylmethyl)amine hydrochloride; N-(4-Fluorobenzyl)-N-(tetrahydrofurfuryl)amine hydrochloride; (4-Fluorobenzyl)(tetrahydro-2-furanylmethyl)ammonium chloride
EINECS	Contact for details

Quality Control

Our (4-Fluorobenzyl)(Tetrahydro-2-Furanylmethyl)Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure compliance with exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.