Description

5-(3,5-Difluorophenyl)Pyridine-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both a pyridine and a difluorophenyl moiety, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl and carboxylic acid groups.
• Ligand Synthesis: Serves as a precursor for creating sophisticated ligands used in catalysis and material science.
• Material Science: Employed in the research and development of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes to study biological pathways and protein functions.

Basic Information

Product Name	5-(3,5-Difluorophenyl)Pyridine-3-Carboxylic Acid
CAS No.	1048267-36-2
Molecular Formula	C12H7F2NO2
Molecular Weight	235.19 g/mol
Synonyms	3-Pyridinecarboxylic acid, 5-(3,5-difluorophenyl)-; 5-(3,5-Difluorophenyl)nicotinic acid; 5-(3,5-Difluorophenyl)-3-pyridinecarboxylic acid; 1048267-36-2; 5-(3,5-Difluorophenyl)pyridine-3-carboxylic acid; Nicotinic acid, 5-(3,5-difluorophenyl)-; AI3-72762
EINECS	Contact for details

Quality Control

Every batch of 5-(3,5-Difluorophenyl)Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (IR, NMR), and impurity profile is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.