Description

5-Bromo-3-Iodo-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functionalized pyrrolopyridine derivative designed for advanced synthetic chemistry. This compound is a critical pharmaceutical intermediate and building block for medicinal chemistry research, enabling the construction of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise, high-purity intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile halogen handles for cross-coupling reactions.
• Agrochemical Synthesis: Serves as a precursor in the development of novel active ingredients for crop protection.
• Organic Electronic Materials: A potential component in the synthesis of organic semiconductors and light-emitting materials.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and protein function.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule assembly.

Basic Information

Product Name	5-Bromo-3-Iodo-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1046831-94-0
Molecular Formula	C14H20BrIN2OSi
Molecular Weight	467.22 g/mol
Synonyms	1-((2-(Trimethylsilyl)ethoxy)methyl)-5-bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-3-iodo-1-[[2-(trimethylsilyl)ethoxy]methyl]-; 5-Bromo-3-iodo-1-SEM-1H-pyrrolo[2,3-b]pyridine; 5-Br-3-I-1-SEM-7-azaindole; SEM-Protected 5-Bromo-3-Iodo-7-azaindole
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Iodo-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.