Description

6-Oxa-1-Aza-Spiro[3,3]Heptane CAS NO 1046153-00-7 is a versatile and highly functionalized spirocyclic building block of significant interest in modern synthetic chemistry. Its unique fused bicyclic structure, containing both oxygen and nitrogen heteroatoms, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in creating constrained, three-dimensional scaffolds to improve drug-like properties.
• Medicinal Chemistry: Used in high-throughput screening libraries and structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Agrochemical Research: Serves as a building block for synthesizing new generations of herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: The spirocyclic framework can be functionalized to create novel chelating ligands and organocatalysts for asymmetric synthesis.
• Material Science Precursor: Potential use in synthesizing specialty polymers and functional materials with specific thermal or chemical properties.
• Chemical Biology Probe: Useful for designing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	6-Oxa-1-Aza-Spiro[3,3]Heptane
CAS No.	1046153-00-7
Molecular Formula	C5H9NO
Molecular Weight	99.13 g/mol
Synonyms	1-Aza-6-oxaspiro[3.3]heptane; 6-Oxa-1-azaspiro[3.3]heptane; 1-Aza-6-oxaspiro[3,3]heptane; 6-Oxa-1-aza-spiro[3.3]heptane; Azaspiro[3.3]heptan-6-one oxime derivative (precursor); 2-Oxa-6-azaspiro[3.3]heptane (isomer); Spirocyclic oxazolidine derivative
EINECS	Contact for details

Quality Control

Our 6-Oxa-1-Aza-Spiro[3,3]Heptane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.