Description

Phenol, 2-[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]- is a specialized chiral oxazoline derivative of phenol, serving as a high-value synthetic intermediate. Its core value lies in its stereochemistry and functional groups, which make it a critical building block for constructing complex molecules with precise spatial orientation. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials. The CAS number for this product is 1045894-43-6.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system or with specific stereochemical requirements.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the chiral center influences biological activity and selectivity.
• Ligand Precursor: Serves as a starting material for the synthesis of chiral oxazoline-based ligands, which are crucial in asymmetric catalysis for producing enantiomerically pure compounds.
• Material Science: Potential monomer or additive in the development of specialized polymers with unique optical or mechanical properties.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, asymmetric reactions, and total synthesis of natural products.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex fragrance molecules, flavors, and other high-value specialty chemicals.

Basic Information

Item	Detail
Product Name	Phenol, 2-[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]-
CAS No.	1045894-43-6
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	(R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol; (4R)-4-Isopropyl-4,5-dihydro-2-(2-hydroxyphenyl)oxazole; 2-[(4R)-4-Isopropyl-4,5-dihydro-1,3-oxazol-2-yl]phenol; (R)-4-Isopropyl-2-(2-hydroxyphenyl)-4,5-dihydrooxazole; Chiral Oxazoline Phenol Derivative; (R)-2-(4,5-Dihydro-4-isopropyloxazol-2-yl)phenol; 2-[(4R)-4,5-Dihydro-4-(propan-2-yl)-1,3-oxazol-2-yl]phenol
EINECS	Contact for details

Quality Control

Our Phenol, 2-[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical identity. Standard quality parameters include assay by HPLC, enantiomeric excess (ee) determination, and control of related substances. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. The container should be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.