Description

3-(3-Bromophenyl)Oxetane is a high-value brominated oxetane derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a phenyl ring substituted with a bromine atom adjacent to a strained oxetane ring, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and plant growth regulators, leveraging the reactivity of the oxetane and bromophenyl groups.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Polymer & Material Science: Incorporated into polymer backbones to modify thermal properties, introduce photoactivity, or create cross-linkable sites for high-performance resins and coatings.
• Chemical Biology Probe Synthesis: Utilized in medicinal chemistry for constructing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific bromo-aryl-oxetane motifs.

Basic Information

Product Name	3-(3-Bromophenyl)Oxetane
CAS No.	1044507-52-9
Molecular Formula	C9H9BrO
Molecular Weight	213.07 g/mol
Synonyms	3-(3-Bromophenyl)oxetane; 3-Bromo-3'-oxetanylbenzene; 3-(3-Bromophenyl)oxacyclobutane; 1-Bromo-3-(oxetan-3-yl)benzene; Oxetane, 3-(3-bromophenyl)-; 3-(m-Bromophenyl)oxetane; 3-(3-Bromophenyl)-1-oxacyclobutane
EINECS	Contact for details

Quality Control

Our 3-(3-Bromophenyl)Oxetane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.