Description

Tetrahydroxysqualene is a hydrogenated derivative of squalene, a naturally occurring triterpene. This compound is valued for its enhanced stability and emollient properties compared to its unsaturated counterpart, making it a versatile ingredient in high-performance formulations. It is primarily utilized in the pharmaceutical and advanced personal care industries where purity and consistency are critical. Tetrahydroxysqualene CAS NO 1043629-23-7 serves as a key intermediate and functional additive for demanding applications.

Application

• Pharmaceutical Excipient: Used as a stable, non-irritating vehicle or penetration enhancer in topical and transdermal drug delivery systems.
• High-End Cosmetic Formulations: Acts as an exceptional emollient and skin-conditioning agent in premium skincare, sun care, and color cosmetics for a non-greasy, silky feel.
• Lipid-Based Drug Delivery: A component in solid lipid nanoparticles (SLNs) and other advanced lipid carriers for improved drug solubility and bioavailability.
• Biochemical Research: Employed as a standard or reagent in lipidomics research and metabolic studies related to cholesterol biosynthesis pathways.
• Lubricant for Medical Devices: Provides lubrication in specialized medical-grade applications due to its biocompatibility and inert nature.
• Stable Carrier Oil: Serves as an oxidation-resistant carrier for sensitive active ingredients in nutraceutical and cosmeceutical products.

Basic Information

Product Name	Tetrahydroxysqualene
CAS No.	1043629-23-7
Molecular Formula	C30H62
Molecular Weight	422.81 g/mol
Synonyms	Perhydrosqualene; Dodecahydrosqualene; Squalane (Note: Commercial 'Squalane' is often a fully hydrogenated mixture); 2,6,10,15,19,23-Hexamethyltetracosane (fully saturated form); Cosbiol; Robane; Tetrahydro-2,6,10,15,19,23-hexamethyltetracosane; Hydrogenated Squalene
EINECS	Contact for details

Quality Control

Our Tetrahydroxysqualene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and cosmetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to guarantee supply reliability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Refractive Index (20°C)	1.450 - 1.455
Specific Gravity (20/20°C)	0.805 - 0.815
Acid Value	≤ 0.5 mg KOH/g
Peroxide Value	≤ 1.0 meq/kg
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.