Description

3,9-Diazaspiro[5.5]Undecane-3-Carboxylic Acid, 8,10-Dioxo-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and diaza structure. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, including potential candidates for neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules and novel APIs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Protease Inhibitor Development: Used in the research and development of inhibitors targeting specific enzymes, given its diaza and carbonyl functionalities.
• Chemical Biology Probes: Utilized for creating specialized molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	3,9-Diazaspiro[5.5]Undecane-3-Carboxylic Acid, 8,10-Dioxo-, 1,1-Dimethylethyl Ester
CAS No.	1043384-94-6
Molecular Formula	C15H24N2O5
Molecular Weight	312.36 g/mol
Synonyms	tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate-8,10-dione; 8,10-Dioxo-3,9-diazaspiro[5.5]undecane-3-carboxylic Acid tert-Butyl Ester; 3-(tert-Butoxycarbonyl)-3,9-diazaspiro[5.5]undecane-8,10-dione; 3-Boc-3,9-diazaspiro[5.5]undecane-8,10-dione; Spirocyclic Diaza Compound 1043384-94-6; 3,9-Diazaspiro[5.5]undecane-8,10-dione, 3-(1,1-dimethylethoxy)carbonyl]-; Boc-protected Spirocyclic Diamine Diketone
EINECS	Contact for details

Quality Control

Our 3,9-Diazaspiro[5.5]Undecane-3-Carboxylic Acid, 8,10-Dioxo-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.