Description

3-[(tert-Butylcarbamoyl)Amino]-4-Chlorobenzoic Acid is a high-purity, functionalized benzoic acid derivative designed for advanced chemical synthesis. This compound serves as a critical building block in pharmaceutical research and development, offering a unique combination of a carboxylic acid group and a protected urea moiety for targeted molecular construction. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, or plant growth regulators that require specific chlorinated aromatic scaffolds.
• Chemical Biology Probe Development: Employed in creating molecular probes and linkers due to its reactive carboxylic acid and protected amine functionalities.
• Peptidomimetic Synthesis: Serves as a constrained amino acid analog for constructing non-peptide bioactive compounds.
• Material Science Precursor: Potential monomer or functionalizing agent for specialty polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-[(tert-Butylcarbamoyl)Amino]-4-Chlorobenzoic Acid
CAS No.	1042774-68-4
Molecular Formula	C12H15ClN2O3
Molecular Weight	270.71 g/mol
Synonyms	4-Chloro-3-[(tert-butylcarbamoyl)amino]benzoic acid; 3-[(tert-Butylaminocarbonyl)amino]-4-chlorobenzoic Acid; 3-(3-tert-Butylureido)-4-chlorobenzoic Acid; 4-Chloro-3-((tert-butylcarbamoyl)amino)benzoic acid; Benzoic acid, 4-chloro-3-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-; 1042774-68-4; tert-Butyl 4-chloro-3-ureidobenzoate precursor
EINECS	Contact for details

Quality Control

Our 3-[(tert-Butylcarbamoyl)Amino]-4-Chlorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.