Description

2,6-Diazaspiro[3.3]heptane, 2-[(4-methylphenyl)sulfonyl]-6-(phenylmethyl)- is a high-value, spirocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a sophisticated scaffold for medicinal chemistry, enabling the rapid exploration of novel three-dimensional chemical space in drug discovery programs. Pharmaceutical researchers and fine chemical manufacturers need this intermediate for developing new therapeutic candidates, particularly in areas requiring constrained, drug-like architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to introduce rigid, spirocyclic motifs that improve potency, selectivity, and metabolic stability.
• Library Synthesis for Drug Discovery: Employed in parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening (HTS).
• Chemical Biology Probe Development: Serves as a core structure for designing molecular probes to study protein function and biological pathways.
• Agrochemical Research: Potential intermediate in the development of new generation herbicides or pesticides with novel modes of action.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers or ligands for catalysis with unique steric properties.

Basic Information

Product Name	2,6-Diazaspiro[3.3]heptane, 2-[(4-Methylphenyl)Sulfonyl]-6-(Phenylmethyl)-
CAS No.	1041026-64-5
Molecular Formula	C19H22N2O2S
Molecular Weight	342.46 g/mol
Synonyms	2-(Tosyl)-6-(benzyl)-2,6-diazaspiro[3.3]heptane; 2,6-Diazaspiro[3.3]heptane, 2-(4-methylbenzenesulfonyl)-6-(phenylmethyl)-; 2-(p-Toluenesulfonyl)-6-benzyl-2,6-diazaspiro[3.3]heptane; 6-Benzyl-2-tosyl-2,6-diazaspiro[3.3]heptane; Tosyl-protected benzyl-diazaspiroheptane; Spirocyclic sulfonamide building block; 1041026-64-5; Benzyl-tosyldiazaspiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our 2,6-Diazaspiro[3.3]heptane derivative is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.