Description

Bis(Butyldi-1-Adamantylphosphine) Palladium Diacetate is a highly specialized, sterically demanding palladium catalyst complex designed for challenging cross-coupling reactions. Its value lies in the exceptional stability and reactivity imparted by the bulky, electron-rich adamantylphosphine ligands, which prevent catalyst decomposition and enable efficient transformations of sterically hindered substrates. This catalyst is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require high-performance catalysts for synthesizing complex organic molecules, particularly where standard catalysts fail.

Application

This advanced palladium catalyst is engineered for high-performance applications in organic synthesis, particularly where standard catalysts are ineffective.

• Pharmaceutical Intermediate Synthesis: Enables key carbon-carbon and carbon-heteroatom bond formations in the production of active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of complex, sterically hindered molecules for novel pesticides and herbicides.
• Buchwald-Hartwig Amination: Highly effective for C-N cross-coupling reactions involving bulky amines and aryl halides.
• Suzuki-Miyaura Coupling: Catalyzes the coupling of aryl/vinyl boronic acids with halides, especially with challenging, deactivated, or sterically crowded substrates.
• Material Science Research: Facilitates the synthesis of conjugated polymers and organic electronic materials requiring precise molecular architecture.
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new chemical space in catalytic transformations.

Basic Information

Product Name	Bis(Butyldi-1-Adamantylphosphine) Palladium Diacetate
CAS No.	1041005-57-5
Molecular Formula	C44H72O4P2Pd
Molecular Weight	857.35 g/mol
Synonyms	Palladium(II) acetate bis(butyldi-1-adamantylphosphine) complex; Diacetatobis(butyldi-1-adamantylphosphine)palladium; Pd(Ad2PBu)2(OAc)2; Buchwald Palladium Precatalyst; Palladium catalyst with cataCXium A; cataCXium A Pd(OAc)2; (Butyldi-1-adamantylphosphine)palladium(II) acetate dimer; Palladium(II) acetate, bis(butyldi-1-adamantylphosphine)-
EINECS	Contact for details

Quality Control

Our Bis(Butyldi-1-Adamantylphosphine) Palladium Diacetate is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analytical characterization, including NMR and Elemental Analysis, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Palladium (Pd) Content	12.0 - 13.0 %
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.