Description

2-Amino-3-[2-(Aminomethyl)Phenyl]Propanoic Acid is a specialized non-proteinogenic amino acid derivative featuring a phenylalanine-like core with an additional aminomethyl substituent. This unique structure makes it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily sought after by research institutions and pharmaceutical developers for the synthesis of novel peptides, peptidomimetics, and bioactive compounds targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neuroscience and metabolic disease research.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified phenylalanine analogs, altering peptide stability, bioavailability, and receptor binding affinity.
• Bioconjugation & Probe Development: Serves as a linker or functional handle in the creation of biochemical probes, diagnostic agents, and antibody-drug conjugates (ADCs) due to its multiple amine groups.
• Chemical Biology Research: Employed in studying enzyme mechanisms, substrate specificity, and as a building block for non-natural amino acids in genetic code expansion experiments.
• Ligand & Catalyst Development: Useful for synthesizing novel chelating ligands and chiral catalysts for asymmetric synthesis applications.

Basic Information

Product Name	2-Amino-3-[2-(Aminomethyl)Phenyl]Propanoic Acid
CAS No.	1040212-39-2
Molecular Formula	C10H14N2O2
Molecular Weight	194.23 g/mol
Synonyms	2-Amino-3-(2-(aminomethyl)phenyl)propanoic acid; 2-Amino-3-[2-(aminomethyl)phenyl]propionic acid; (2S)-2-Amino-3-[2-(aminomethyl)phenyl]propanoic acid (if stereospecific); 2-(Aminomethyl)-D,L-homophenylalanine; β-(2-Aminomethylphenyl)-β-alanine; 1040212-39-2; 2-Amino-3-(2-aminomethylphenyl)propionic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-3-[2-(Aminomethyl)Phenyl]Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis, and spectroscopic identification to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing batch-specific data is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.