Description

(R)-4,12-Bis(4-Methoxyphenyl)-[2.2]-Paracyclophane(1,5-Cyclooctadiene)Rhodium(I) Tetrafluoroborate is a highly specialized chiral organometallic complex, primarily valued as a sophisticated asymmetric catalyst precursor. Its core value proposition lies in enabling high enantioselectivity and catalytic efficiency in critical synthetic transformations, which is essential for producing optically pure intermediates. This product is specifically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic routes and manufacturing high-value chiral compounds.

Application

• Asymmetric Hydrogenation: A key catalyst precursor for the enantioselective reduction of prochiral olefins, enamides, and ketones to produce chiral building blocks for active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Enables the synthesis of complex, single-enantiomer molecules critical for drug discovery and development programs.
• Agrochemical Research: Used in the development of chiral herbicides, fungicides, and pesticides where specific stereochemistry is required for biological activity.
• Fine Chemical Manufacturing: Facilitates the production of high-value specialty chemicals and flavors & fragrances with precise stereochemical control.
• Academic & Industrial R&D: Serves as a valuable tool for methodological development in asymmetric catalysis and organometallic chemistry.
• Ligand Screening & Catalyst Optimization: The paracyclophane backbone provides a unique, rigid chiral environment for studying structure-activity relationships in catalysis.

Basic Information

Item	Details
Product Name	(R)-4,12-Bis(4-Methoxyphenyl)-[2.2]-Paracyclophane(1,5-Cyclooctadiene)Rhodium(I) Tetrafluoroborate
CAS No.	1038932-67-0
Molecular Formula	C36H36BF4O2Rh
Molecular Weight	690.39 g/mol
Synonyms	(R)-Walphos-Rh(COD)BF4; (R)-4,12-Bis(4-methoxyphenyl)-4,12-dihydro-4,12[1',2']-benzeno[2.2]paracyclophane(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; (R)-[2.2]Paracyclophane-based Rhodium(I) Catalyst; Rhodium(I)-(R)-Walphos complex; Asymmetric hydrogenation catalyst precursor; Chiral rhodium paracyclophane complex; (R)-Walphos ligand rhodium COD tetrafluoroborate salt
EINECS	Contact for details

Quality Control

Every batch of our (R)-4,12-Bis(4-Methoxyphenyl)-[2.2]-Paracyclophane(1,5-Cyclooctadiene)Rhodium(I) Tetrafluoroborate is manufactured and tested under strict quality management systems to ensure exceptional purity, enantiomeric excess, and batch-to-batch consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay, chiral purity, and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at 2-8°C in a dry, cool place. This material is hygroscopic (moisture-sensitive) and light-sensitive. Allow the container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Rhodium Content	14.5 - 15.5 %
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.