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6-Fluoroimidazo[1,2-A]Pyridine-2-Methanol CAS NO 1038827-63-2


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CAS No.:1038827-63-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Fluoroimidazo[1,2-A]Pyridine-2-Methanol is a high-value fluorinated heterocyclic building block, specifically a substituted imidazopyridine derivative. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating new drug candidates, particularly in areas like kinase inhibitors and central nervous system (CNS) agents.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates targeting various therapeutic areas.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to modulate pharmacokinetic properties.
  • Kinase Inhibitor Synthesis: Serves as a core scaffold or substituent in the design of potent and selective kinase inhibitors for oncology.
  • Agrochemical Development: Employed in the research of novel fluorinated active ingredients for crop protection.
  • Material Science Precursor: Potential use in the synthesis of advanced organic materials and ligands for catalysis.
  • Bioconjugation & Probe Development: Useful for creating fluorescent probes or tagged molecules for biological imaging and diagnostic applications.

Basic Information

Item Details
Product Name 6-Fluoroimidazo[1,2-A]Pyridine-2-Methanol
CAS No. 1038827-63-2
Molecular Formula C8H7FN2O
Molecular Weight 166.15 g/mol
Synonyms 6-Fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridine; (6-Fluoroimidazo[1,2-a]pyridin-2-yl)methanol; 2-(Hydroxymethyl)-6-fluoroimidazo[1,2-a]pyridine; 6-Fluoroimidazo[1,2-a]pyridine-2-carbinol; 1038827-63-2; 6-Fluoro-2-imidazo[1,2-a]pyridinemethanol
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Quality Control

Our 6-Fluoroimidazo[1,2-A]Pyridine-2-Methanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Retention time corresponds to reference standard
Identification (NMR) Spectrum consistent with structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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