Description

3-[1-(tert-Butoxycarbonyl)Piperidin-4-Ylcarbamoyl]Benzoic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, enabling the development of targeted therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, particularly in areas requiring sophisticated piperidine-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Protease Inhibitor Research: Used in the development of protease inhibitors, where the tert-butoxycarbonyl (Boc) and benzoic acid moieties are essential for activity and selectivity.
• Peptidomimetic Chemistry: Serves as a core component in the design and synthesis of peptidomimetics, molecules that mimic peptides but with enhanced stability and bioavailability.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying enzyme function and protein-protein interactions within biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.
• Academic & Industrial R&D: Utilized in research laboratories for exploring new synthetic routes and developing compound libraries for high-throughput screening.

Basic Information

Product Name	3-[1-(tert-Butoxycarbonyl)Piperidin-4-Ylcarbamoyl]Benzoic Acid
CAS No.	1038409-56-1
Molecular Formula	C18H24N2O5
Molecular Weight	348.40 g/mol
Synonyms	3-({[1-(tert-Butoxycarbonyl)piperidin-4-yl]carbamoyl})benzoic Acid; 3-((1-Boc-piperidin-4-yl)carbamoyl)benzoic Acid; 1-Boc-4-[(3-carboxybenzoyl)amino]piperidine; Benzoic acid, 3-[[[1-[(1,1-dimethylethoxy)carbonyl]-4-piperidinyl]amino]carbonyl]-; 3-(1-Boc-piperidine-4-carboxamido)benzoic Acid; 3-Carboxy-N-(1-Boc-4-piperidyl)benzamide
EINECS	Contact for details

Quality Control

Our 3-[1-(tert-Butoxycarbonyl)Piperidin-4-Ylcarbamoyl]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.