Description

6-Azaspiro[2.5]Octane Hydrochloride is a high-purity, versatile spirocyclic amine building block essential for modern pharmaceutical and agrochemical research. Its unique constrained spirocyclic structure makes it a valuable scaffold for designing novel bioactive molecules with improved metabolic stability and target selectivity. This intermediate is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and crop protection industries for the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of central nervous system (CNS) active drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its spirocyclic framework.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes, activity-based probes (ABPs), and fragment-based drug discovery libraries.
• Material Science: Potential precursor for specialty polymers, ligands for catalysis, and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	6-Azaspiro[2.5]Octane Hydrochloride
CAS No.	1037834-62-0
Molecular Formula	C7H14ClN
Molecular Weight	147.65 g/mol
Synonyms	6-Azaspiro[2.5]octane, hydrochloride; 1-Azaspiro[2.5]octane hydrochloride; 6-Azaspiro[2.5]octane HCl; Azaspirooctane hydrochloride; Spiro[cyclopropane-1,6'-bicyclo[3.2.0]heptane] hydrochloride; 1-Azoniabicyclo[4.1.0]heptane chloride
EINECS	Contact for details

Quality Control

Our 6-Azaspiro[2.5]Octane Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.