Description

2-Chloro-1-{1H-Pyrrolo[2,3-B]Pyridin-3-Yl}Propan-1-One is a high-purity, advanced pharmaceutical intermediate with a distinct pyrrolopyridine core structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing targeted therapies and kinase inhibitors.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for kinase-targeted drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery programs focused on oncology and neurological disorders.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition mechanisms and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Acts as a specialized building block for synthesizing complex heterocyclic compounds in custom synthesis and contract manufacturing.

Basic Information

Product Name	2-Chloro-1-{1H-Pyrrolo[2,3-B]Pyridin-3-Yl}Propan-1-One
CAS No.	1037152-84-3
Molecular Formula	C10H9ClN2O
Molecular Weight	208.64 g/mol
Synonyms	2-Chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)propan-1-one; 1-Propanone, 2-chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)-; 3-(2-Chloropropanoyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-(2-chloro-1-oxopropyl)-; 7-Azaindole-3-propionyl chloride derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-{1H-Pyrrolo[2,3-B]Pyridin-3-Yl}Propan-1-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.